Anna University 2013 Regulation - BM6005 Bio Informatics - Syllabus - Download

UNIT I INTRODUCTION 9

Need for Bioinformatics technologies – Overview of Bioinformatics technologies Structural bioinformatics – Data format and processing – Secondary resources and applications – Role of Structural bioinformatics - Biological Data Integration System.

UNIT II DATAWAREHOUSING AND DATAMINING IN BIOINFORMATICS 9

Bioinformatics data – Data warehousing architecture – data quality – Biomedical data analysis – DNA data analysis –
Protein data analysis – Machine learning – Neural network architecture and applications in bioinformatics.

UNIT III MODELING FOR BIOINFORMATICS 9

Hidden Markov modeling for biological data analysis – Sequence identification –Sequence classification – multiple 
alignment generation – Comparative modeling –Protein modeling – genomic modeling – Probabilistic modeling –
Bayesian networks – Boolean networks - Molecular modeling – Computer programs for molecular modeling.

UNIT IV PATTERN MATCHING AND VISUALIZATION 9

Gene regulation – motif recognition – motif detection – strategies for motif detection – Visualization – Fractal analysis –
DNA walk models – one dimension – two dimension – higher dimension – Game representation of Biological sequences 
– DNA, Protein, Amino acid sequences.

UNIT V MICROARRAY ANALYSIS 9

Microarray technology for genome expression study – image analysis for data extraction – preprocessing – segmentation – gridding – spot extraction – normalization, filtering – cluster analysis – gene network analysis – Compared Evaluation of Scientific Data Management Systems – Cost Matrix – Evaluation model - Benchmark – Tradeoffs.

Anna University 2013 Regulation - BM6005 Bio Informatics - Syllabus - Download